Assay
Age
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Western blot
10.5 DPC
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Erbb2 erb-b2 receptor tyrosine kinase 2 (Synonyms: c-erbB2, c-neu, ErbB-2, HER2, HER-2, l11Jus8, mKIAA3023, Neu, Neu oncogene) | |
Results | Reference |
1* | J:74283 Chan R, Hardy WR, Laing MA, Hardy SE, Muller WJ, The Catalytic Activity of the ErbB-2 Receptor Tyrosine Kinase Is Essential for Embryonic Development. Mol Cell Biol. 2002 Feb;22(4):1073-8 |
1* | J:45302 Erickson SL, O'Shea KS, Ghaboosi N, Loverro L, Frantz G, Bauer M, Lu LH, Moore MW, ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice. Development. 1997 Dec;124(24):4999-5011 |
1 | J:239830 Hirai M, Arita Y, McGlade CJ, Lee KF, Chen J, Evans SM, Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017 Feb 01;127(2):569-582 |
1 | J:312427 Kim K, Lee D, ERBB3-dependent AKT and ERK pathways are essential for atrioventricular cushion development in mouse embryos. PLoS One. 2021;16(10):e0259426 |
1* | J:29973 Lee KF, Simon H, Chen H, Bates B, Hung MC, Hauser C, Requirement for neuregulin receptor erbB2 in neural and cardiac development [see comments]. Nature. 1995 Nov 23;378(6555):394-8 |
1 | J:64067 Nebigil CG, Choi DS, Dierich A, Hickel P, Le Meur M, Messaddeq N, Launay JM, Maroteaux L, Serotonin 2B receptor is required for heart development. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9508-13 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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